Antipyretic and antinociceptive effects of nauclea. Pdf pharmacological evidence favouring the use of nauclea. Nauclea latifolia, also named nauclea esculentus, is one of the medicinal plants used in africa. Neurobehavioural effects of nauclea latifolia and emilia sonchifolia. In vitro effect of nauclea latifolia leaf extract in ethanol, hot water and cold water at concentrations of 400, 200, 100 and 50mgml were tested on some pathogenic bacteria such as staphylococcus aureus, streptococcus pyogenes, escherichia.
Nauclea latifolia had been reported to have antimicrobial properties. View of antimicrobial properties of the methanolic. Sarcocephalus latifolius, rubiaceae, commonly called the african pincushion tree, is a plant widely. The structures with absolute configurations of the new compounds were identified on the basis of 1d. In vitro study of nutritional and antioxidant properties of methanol extract of nauclea latifolia root bark. In vitro study of nutritional and antioxidant properties. We will indeed be offering the african herb, nauclea latifol. Nebraska department of agriculture, bureau of plant industry. Nauclea latifolia in world checklist of selected plant families. Malignacies are still a major public concern worldwide and despite the intensive search for new chemotherapeutic agents, treatment still remains a challenging issue.
The plant nauclea latifolia is widely used in the southern parts of nigeria for the treatment of malaria. Nauclea latifolia is a small evergreen tree or straggling shrub with leaves rounded. Nauclea latifolia is an evergreen multistemmed shrub or a tree. The study evaluated the protective effects of nls extract supplemented along with valproic acid on oxidative stress markers, and neuron specific enolase nse and b cell lymphoma 2 bcl. This page was last edited on 17 february 2019, at 14. Cytotoxicity of selected cameroonian medicinal plants and.
Rubiaceae locally nicknamed chloroquine leaf is an evergreen multistemmed medicinal plant. Nauclea latifolia induced hypothermia and had antipyretic effects in mice. In vitro study on the antioxidant potentials of the leaves and fruits. African tree, nauclea latifolia, contains tramadol on. We do not intend the plant list to be complete for names of infraspecific rank. The antinociceptive effect exhibited by the decoction in the formalin test was reversed by the systemic administration of naloxone, n. All structured data from the file and property namespaces is available under the creative commons cc0 license.
It is locally called egbesi in yoruba, ubuluino in igbo, marga in hausa and mbomibon in ibibio. For more multimedia, look at naucleeae on wikimedia commons. Nauclea latifolia has an open canopy and terminal spherical head lined cymes of. Rubiaceae is a valuable medicinal plant that is widespread in.
It grows to a maximum of around 30 m 98 ft in height and has large glossy leaves. Their structures were elucidated based on the analysis of their nmr and ms data. Evaluation of antidiabetic activity of nauclea latifolia. Anticonvulsant, anxiolytic, and sedative properties of the. It is a widely distributed savanna plant native to africa and asia. Pdf in vivo antiplasmodial activities of nauclea latifolia. This page was last edited on 20 december 2019, at 14. The species are evergreen trees or shrubs that are native to the paleotropics. Germain sotoing ta we, elisabeth ngo bum, emmanuel talla, th eophile dimo, amadou dawe, val erie sinniger, bruno bonaz. Introduction compounds which exert various physiological effects of therapeutic value are collectively known as drugs 1.
Histomophological study of the effect of ethanolic extract. List of various diseases cured by nauclea orientalis. Pdf nauclea latifolia smith is used traditionally in the treatment of uncomplicated malaria and painful conditions among its several. This study was carried out to assess the in vitro antioxidant, antiinflammatory and antidiabetic effects of nauclea latifolia sm. Only 10% of plants have been studied for their pharmacological properties. Nauclea latifolia, antimicrobial analysis, structural elucidation, ftir, uvspectrum, nmr, and funbacta cream 1. Nauclea latifolia african peach pfaf plant database. The people of ogidi in idemili north local government area of anambra state, nigeria, used it to treat wound infections. Iv foreword although subsaharan africa and the indian ocean islands contain about 60,000 of the worlds higher plant species, roughly a quarter of the worlds total, less than 8%. Ogugua victor nwadiogbu 1, njoku ou 1, egba simeon ikechukw 2, robert ikechukw uroko 2, ignatius glory1 1department of biochemistry, faculty of biological sciences, university of nigeria, nsukka, nigeria 2department of biochemistry, college of natural sciences, michael okpara. Nauclea latifolia aqueous leaf extract eliminates hepatic. Latifolia is native to africa and asia gidado et al. Synthetic drug found in nature research chemistry world. Indole alkaloids from the leaves of nauclea officinalis.
Nauclea latifolia is a valuable medicinal plant that is widespread in the humid tropical rainforest zone or in savannah woodlands of west and central africa. Files are available under licenses specified on their description page. Mitschercomprehensive survey of indigenous iraqi plants for potential economic value. It is widely distributed throughout the forest and tropical forests of benin, burkina faso, cameroon, democratic republic of congo, ghana and nigeria lamidi et al. Nauclea latifolia commonly known as pin cushion tree is a straggling shrub or small spreading tree that belongs to the family rubiaceae and to the class magnoliopsida dicotyledons. The plant list includes a further 10 scientific plant names of infraspecific rank for the genus nauclea. It has many common names, including bur tree, canary wood, leichhardt pine and yellow cheesewood.
Antimicrobial analysis and structural elucidation of. This article is from bmc complementary and alternative medicine, volume. Novel indole alkaloids from nauclea latifolia and their. Nauclea orientalis herb uses, benefits, cures, side. Inhibitive action of ethanol extracts from nauclea.
Pdf traditional uses, phytochemistry and pharmacological. Also known as pin cushion tree and bishops head, it is a struggling shrub or small tree native to tropical africa and asia 7. Hot water extracts of the leaves and fruits of nauclea latifolia were assessed for their total polyphenolic, flavanol, and flavonol contents as well as 1diphenyl2picrylhydrazyl dpph scavenging. The stem bark, the leaves, the roots, and the fruit of this plant are used to treat various types of. This study is therefore aimed at determining this claim ie antimicrobial effect of this plant using the stem bark of nauclea latifolia. Nauclea latifolia is in stock with a 4 ounce limit, per customer, per order. Three new indole alkaloids, named naucleamide g 1, and nauclealomide b and c 5 and 6, were isolated from the nbuohsoluble fraction of an etoh extract of the leaves of nauclea officinalis, together with three known alkaloids, paratunamide c 2, paratunamide d 3 and paratunamide a 4. Uses, benefits, cures, side effects, nutrients in nauclea orientalis. It is found in the forest and fringe tropical forest. Tramadol, a drug formerly only thought to exist as a synthetic, has been found in nature. Hot water extracts of the leaves and fruits of nauclea latifolia were assessed for their total polyphenolic, flavanol, and flavonol contents as well. Family species anacardiaceae mangifera indica mango sclerocarya birrea marula plum anisophyllaceae anisopyllea laurina annonaceae annona cherimola cherimoya a.
It refers to the resemblance of the cells of the capsule to a ships hull. Us20160039742a1 extraction of tramadol from nauclea. Nauclea latifolia smith rubiaceae exerts antinociceptive e ects in neuropathic pain induced by chronic constriction injury of the sciatic nerve. The bark of nauclea latifolia contains tramadol at medicinal concentrations. The plant decoction produced significant antinociceptive activity in all analgesia animal models used. The plant list includes 220 scientific plant names of species rank for the genus nauclea. The structures of these compounds were elucidated by. The terminal vegetative buds are usually strongly flattened. The board of trustees of the royal botanic gardens, kew. Additionally, the extraction of the synthetic analgesic tra smith, nauclea pobeguinii hua ex pobeg. Nauclea latifolia belongs to the family of rubiaceae, the common name include pin cushion tree or african peach. Screening for antimicrobial activity and for alkaloids of nauclea latifolia.
Bioactive screening and in vitro antioxidant assessment of nauclea latifolia leaf decoction franklyn nonso iheagwam 1, 2, a, emmanuel israel nsedu 1, kazeem oyindamola kayode 1, opeyemi christianah emiloju 1, 2, olubanke olujoke ogunlana 1, 2 and shalom nwodo chinedu 1, 2 1 department of biochemistry, college of science and technology, covenant university, canaanland, p. It also publishes academic books and conference proceedings. Nauclea latifolia is a deciduous tree growing to 10 m 32ft by 10 m 32ft at a medium rate. Three previously undescribed indole alkaloids, named latifolianine a 1 and latifoliaindoles a and b 2 and 3, along with 10 known compounds 4, were isolated from the heartwood of nauclea latifolia. First marketed in 1977, tramadol is frequently used to relieve moderate to moderatelysevere pain. Antimicrobial properties of the ethyl acetate extract of. Nauclea is a genus of flowering plants in the family rubiaceae. The generic name is derived from the ancient greek words naus, meaning ship and kleio, meaning to close. These are primarily included because names of species rank are synonyms. The percentage glycaemic change on nondiabetic rats following. Nauclea latifolia smith, a shrub belonging to the family rubiaceae is a very popular medicinal plant in cameroon and neighboring countries where it is used to treat jaundice, yellow fever. A research paper, showing the presence of a natural painrelieving opoid in the bark and roots of nauclea latifolia. Latifolianine a 1 represents an unusual and unprecedented monoterpene indole alkaloid unit condensed with. In vitro study on the antioxidant potentials of the leaves.
Nauclea latifolia contained alkaloid, saponins, flavonoids, cardiac glycosides and steroids while tannins and terpenoids were absent. This work was designed to assess the cytotoxicity of six selected cameroonian medicinal plants, including nauclea pobeguinii and its constituents 3acetoxy11oxours12ene 1, pcoumaric acid 2, citric acid trimethyl ester 3. Roots of nauclea latifolia are used in nigeria for the treatment of hypertension. Table 2 shows the effect of chloroform extract of nauclea latifolia and glibenclamide on blood glucose level of nondiabetic rats. Extracts of the plant have exhibited activity against escherichia coli, shigella flexneri, salmonella typhi and staphylococcus aureus which are responsible for gastroenteritis in children303. Chemical studies on the crude meoh extract of stems and barks of nauclea latifolia resulted in the isolation of five new indole alkaloids, latifoliamides ae 15, resp. A 4 ounce bottle should be close to a one month supply. Nauclea latifolia smith rubiaceae exerts antinociceptive. This study was carried out to investigate the in vitro antioxidant potentials of the leaves and fruits of nauclea latifolia, a straggling shrub or small tree, native to tropical africa and asia. Antimicrobial and phytochemical screening of nauclea. Rubiaceae is a spreading, evergreen, multistemmed shrub or small tree native to tropical africa and asia gidado et al. Diagram showing the leaves, fruit and flower of nauclea latifolia smith fern, 2014. It bears spherical clusters of fragrant flowers that develop into golf ballsized edible but.
Preliminary studies of blood pressure lowering effect of nauclea. Nauclea latifolia smith, a shrub belonging to the family. How nauclea orientalis is effective for various diseases is listed in repertory format. Traditional medicine in many areas of the world relies on the use of a wide variety of plant species. Rubiaceae inferred from molecular its, rbcl, and trntf and morphological data american journal of botany 89. Constituents from nauclea latifolia with antihaemophilus. Herbal medicine sometimes referred to as herbalism or botanical. Names of nauclea orientalis in various languages of the world are also given. In vitro antiherpes simplex virus activity of crude. Nauclea orientalis is a species of tree in the family rubiaceae, native to southeast asia, new guinea, and australia. Science and education publishing is an academic publisher of open access journals. Plants profile for typha latifolia broadleaf cattail.